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Osteoponin Promoter Controlled by DNA Methylation: Aberrant Methylation in Cloned Porcine Genome
Cloned animals usually exhibited many defects in physical characteristics or aberrant epigenetic reprogramming, especially in some important organ development. Osteoponin (OPN) is an extracellular-matrix protein involved in heart and bone development and diseases. In this study, we investigated the...
Autores principales: | Shen, Chih-Jie, Tsou, Yung-An, Chen, Hsiao-Ling, Huang, Hung-Jin, Wu, Shinn-Chih, Cheng, Winston T. K., Chen, Calvin Yu-Chian, Chen, Chuan-Mu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102072/ https://www.ncbi.nlm.nih.gov/pubmed/25101273 http://dx.doi.org/10.1155/2014/327538 |
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