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Signaling Domain of Sonic Hedgehog as Cannibalistic Calcium-Regulated Zinc-Peptidase
Sonic Hedgehog (Shh) is a representative of the evolutionary closely related class of Hedgehog proteins that have essential signaling functions in animal development. The N-terminal domain (ShhN) is also assigned to the group of LAS proteins (LAS = Lysostaphin type enzymes, D-Ala-D-Ala metalloprotea...
Autores principales: | Rebollido-Rios, Rocio, Bandari, Shyam, Wilms, Christoph, Jakuschev, Stanislav, Vortkamp, Andrea, Grobe, Kay, Hoffmann, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102407/ https://www.ncbi.nlm.nih.gov/pubmed/25033298 http://dx.doi.org/10.1371/journal.pcbi.1003707 |
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