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Leishmania amazonensis Amastigotes Highly Express a Tryparedoxin Peroxidase Isoform That Increases Parasite Resistance to Macrophage Antimicrobial Defenses and Fosters Parasite Virulence

Professional phagocytes generate a myriad of antimicrobial molecules to kill invading microorganisms, of which nitrogen oxides are integral in controlling the obligate intracellular pathogen Leishmania. Although reactive nitrogen species produced by the inducible nitric oxide synthase (iNOS) can pro...

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Detalles Bibliográficos
Autores principales:	Henard, Calvin A., Carlsen, Eric D., Hay, Christie, Kima, Peter E., Soong, Lynn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102420/ https://www.ncbi.nlm.nih.gov/pubmed/25033301 http://dx.doi.org/10.1371/journal.pntd.0003000

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