Cargando…

Recombinant Antigens Expressed in Pichia pastoris for the Diagnosis of Sleeping Sickness Caused by Trypanosoma brucei gambiense

BACKGROUND: Screening tests for gambiense sleeping sickness, such as the CATT/T. b. gambiense and a recently developed lateral flow tests, are hitherto based on native variant surface glycoproteins (VSGs), namely LiTat 1.3 and LiTat 1.5, purified from highly virulent trypanosome strains grown in rod...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rogé, Stijn, Van Nieuwenhove, Liesbeth, Meul, Magali, Heykers, Annick, Brouwer de Koning, Annette, Bebronne, Nicolas, Guisez, Yves, Büscher, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102443/ https://www.ncbi.nlm.nih.gov/pubmed/25032684 http://dx.doi.org/10.1371/journal.pntd.0003006

Ejemplares similares

Identification of Peptide Mimotopes of Trypanosoma brucei gambiense Variant Surface Glycoproteins
por: Van Nieuwenhove, Liesbeth Carolien, et al.
Publicado: (2011)

Identification of Mimotopes with Diagnostic Potential for Trypanosoma brucei gambiense Variant Surface Glycoproteins Using Human Antibody Fractions
por: Van Nieuwenhove, Liesbeth, et al.
Publicado: (2012)

Luminescent multiplex viability assay for Trypanosoma brucei gambiense
por: Van Reet, Nick, et al.
Publicado: (2013)

Expression of Trypanosoma brucei gambiense Antigens in Leishmania tarentolae. Potential for Use in Rapid Serodiagnostic Tests (RDTs)
por: Rooney, Barrie, et al.
Publicado: (2015)

Specificity of malaria rapid diagnostic tests is affected by Trypanosoma brucei gambiense sleeping sickness
por: Gillet, Philippe, et al.
Publicado: (2012)

Deep kinetoplast genome analyses result in a novel molecular assay for detecting Trypanosoma brucei gambiense-specific minicircles
por: Geerts, Manon, et al.
Publicado: (2022)

Cerebrospinal Fluid Neopterin as Marker of the Meningo-Encephalitic Stage of Trypanosoma brucei gambiense Sleeping Sickness
por: Tiberti, Natalia, et al.
Publicado: (2012)

Isolation of Trypanosoma brucei gambiense from Cured and Relapsed Sleeping Sickness Patients and Adaptation to Laboratory Mice
por: Pyana, Patient Pati, et al.
Publicado: (2011)

Untreated Human Infections by Trypanosoma brucei gambiense Are Not 100% Fatal
por: Jamonneau, Vincent, et al.
Publicado: (2012)

Target product profile: diagnostic test for Trypanosoma brucei gambiense
por: Priotto, Gerardo, et al.
Publicado: (2023)

NECT Is Next: Implementing the New Drug Combination Therapy for Trypanosoma brucei gambiense Sleeping Sickness
por: Yun, Oliver, et al.
Publicado: (2010)

Target product profile: Trypanosoma brucei gambiense test to verify elimination
por: Priotto, Gerardo, et al.
Publicado: (2023)

Neopterin Is a Cerebrospinal Fluid Marker for Treatment Outcome Evaluation in Patients Affected by Trypanosoma brucei gambiense Sleeping Sickness
por: Tiberti, Natalia, et al.
Publicado: (2013)

Silent Human Trypanosoma brucei gambiense Infections around the Old Gboko Sleeping Sickness Focus in Nigeria
por: Solomon Ngutor, Karshima, et al.
Publicado: (2016)

Aquaporin 2 Mutations in Trypanosoma brucei gambiense Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
por: Graf, Fabrice E., et al.
Publicado: (2013)

Melarsoprol Sensitivity Profile of Trypanosoma brucei gambiense Isolates from Cured and Relapsed Sleeping Sickness Patients from the Democratic Republic of the Congo
por: Pyana Pati, Patient, et al.
Publicado: (2014)

Identification of Trypanosoma brucei gambiense in naturally infected dogs in Nigeria
por: Umeakuana, Paschal Ugochukwu, et al.
Publicado: (2019)

Target product profile: Trypanosoma brucei gambiense test for low-prevalence settings
por: Priotto, Gerardo, et al.
Publicado: (2023)

Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections
por: Bucheton, B, et al.
Publicado: (2011)

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense
por: Cooper, Anneli, et al.
Publicado: (2016)

Neural Damage in Experimental Trypanosoma brucei gambiense Infection: The Suprachiasmatic Nucleus
por: Tesoriero, Chiara, et al.
Publicado: (2018)

Three Drug Combinations for Late-Stage Trypanosoma brucei gambiense Sleeping Sickness: A Randomized Clinical Trial in Uganda
por: Priotto, Gerardo, et al.
Publicado: (2006)

Neopterin and CXCL-13 in Diagnosis and Follow-Up of Trypanosoma brucei gambiense Sleeping Sickness: Lessons from the Field in Angola
por: Bonnet, Julien, et al.
Publicado: (2019)

The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
por: Capewell, Paul, et al.
Publicado: (2013)

Single nucleotide polymorphisms and copy-number variations in the Trypanosoma brucei repeat (TBR) sequence can be used to enhance amplification and genotyping of Trypanozoon strains
por: Van Reet, Nick, et al.
Publicado: (2021)

The Genome Sequence of Trypanosoma brucei gambiense, Causative Agent of Chronic Human African Trypanosomiasis
por: Jackson, Andrew P., et al.
Publicado: (2010)

The elimination of Trypanosoma brucei gambiense? Challenges of reservoir hosts and transmission cycles: Expect the unexpected
por: Mehlitz, D., et al.
Publicado: (2019)

Trypanosoma brucei gambiense-iELISA: A Promising New Test for the Post-Elimination Monitoring of Human African Trypanosomiasis
por: Geerts, Manon, et al.
Publicado: (2020)

A mathematical model for evaluating the role of trypanocide treatment of cattle in the epidemiology and control of Trypanosoma brucei rhodesiense and T. b. gambiense sleeping sickness in Uganda
por: Meisner, Julianne, et al.
Publicado: (2019)

Trypanosoma brucei gambiense Adaptation to Different Mammalian Sera Is Associated with VSG Expression Site Plasticity
por: Cordon-Obras, Carlos, et al.
Publicado: (2013)

Trypanosoma brucei gambiense Infections in Mice Lead to Tropism to the Reproductive Organs, and Horizontal and Vertical Transmission
por: Biteau, Nicolas, et al.
Publicado: (2016)

Midgut expression of immune-related genes in Glossina palpalis gambiensis challenged with Trypanosoma brucei gambiense
por: Hamidou Soumana, Illiassou, et al.
Publicado: (2014)

Unusual MRI Findings in African Trypanosoma brucei gambiense Trypanosomiasis: Dentate Nuclei and Hypothalamic Lesions
por: Boukobza, Monique, et al.
Publicado: (2020)

Immunoinformatic design of a putative multi-epitope vaccine candidate against Trypanosoma brucei gambiense
por: Danazumi, Ammar Usman, et al.
Publicado: (2022)

Molecular identification of Trypanosoma brucei gambiense in naturally infected pigs, dogs and small ruminants confirms domestic animals as potential reservoirs for sleeping sickness in Chad
por: Vourchakbé, Joël, et al.
Publicado: (2020)

Chimerization at the AQP2–AQP3 locus is the genetic basis of melarsoprol–pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates
por: Graf, Fabrice E., et al.
Publicado: (2015)

Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum
por: Young, Rosanna, et al.
Publicado: (2008)

Differences between Trypanosoma brucei gambiense Groups 1 and 2 in Their Resistance to Killing by Trypanolytic Factor 1
por: Capewell, Paul, et al.
Publicado: (2011)

The miRNA and mRNA Signatures of Peripheral Blood Cells in Humans Infected with Trypanosoma brucei gambiense
por: Leong, Smiths, et al.
Publicado: (2013)

Neural Damage in Experimental Trypanosoma brucei gambiense Infection: Hypothalamic Peptidergic Sleep and Wake-Regulatory Neurons
por: Laperchia, Claudia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3d3t5fl87vihu5h9fa37r18mtu