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NCI-60 Whole Exome Sequencing and Pharmacological CellMiner Analyses

Exome sequencing provides unprecedented insights into cancer biology and pharmacological response. Here we assess these two parameters for the NCI-60, which is among the richest genomic and pharmacological publicly available cancer cell line databases. Homozygous genetic variants that putatively aff...

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Detalles Bibliográficos
Autores principales: Reinhold, William C., Varma, Sudhir, Sousa, Fabricio, Sunshine, Margot, Abaan, Ogan D., Davis, Sean R., Reinhold, Spencer W., Kohn, Kurt W., Morris, Joel, Meltzer, Paul S., Doroshow, James H., Pommier, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102467/
https://www.ncbi.nlm.nih.gov/pubmed/25032700
http://dx.doi.org/10.1371/journal.pone.0101670