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Edaravone Protects against Methylglyoxal-Induced Barrier Damage in Human Brain Endothelial Cells
BACKGROUND: Elevated level of reactive carbonyl species, such as methylglyoxal, triggers carbonyl stress and activates a series of inflammatory responses leading to accelerated vascular damage. Edaravone is the active substance of a Japanese medicine, which aids neurological recovery following acute...
Autores principales: | Tóth, Andrea E., Walter, Fruzsina R., Bocsik, Alexandra, Sántha, Petra, Veszelka, Szilvia, Nagy, Lajos, Puskás, László G., Couraud, Pierre-Olivier, Takata, Fuyuko, Dohgu, Shinya, Kataoka, Yasufumi, Deli, Mária A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102474/ https://www.ncbi.nlm.nih.gov/pubmed/25033388 http://dx.doi.org/10.1371/journal.pone.0100152 |
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