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Effects of Low-Level Deuterium Enrichment on Bacterial Growth
Using very precise (±0.05%) measurements of the growth parameters for bacteria E. coli grown on minimal media, we aimed to determine the lowest deuterium concentration at which the adverse effects that are prominent at higher enrichments start to become noticeable. Such a threshold was found at 0.5%...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102507/ https://www.ncbi.nlm.nih.gov/pubmed/25033078 http://dx.doi.org/10.1371/journal.pone.0102071 |
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author | Xie, Xueshu Zubarev, Roman A. |
author_facet | Xie, Xueshu Zubarev, Roman A. |
author_sort | Xie, Xueshu |
collection | PubMed |
description | Using very precise (±0.05%) measurements of the growth parameters for bacteria E. coli grown on minimal media, we aimed to determine the lowest deuterium concentration at which the adverse effects that are prominent at higher enrichments start to become noticeable. Such a threshold was found at 0.5% D, a surprisingly high value, while the ultralow deuterium concentrations (≤0.25% D) showed signs of the opposite trend. Bacterial adaptation for 400 generations in isotopically different environment confirmed preference for ultralow (≤0.25% D) enrichment. This effect appears to be similar to those described in sporadic but multiple earlier reports. Possible explanations include hormesis and isotopic resonance phenomena, with the latter explanation being favored. |
format | Online Article Text |
id | pubmed-4102507 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-41025072014-07-21 Effects of Low-Level Deuterium Enrichment on Bacterial Growth Xie, Xueshu Zubarev, Roman A. PLoS One Research Article Using very precise (±0.05%) measurements of the growth parameters for bacteria E. coli grown on minimal media, we aimed to determine the lowest deuterium concentration at which the adverse effects that are prominent at higher enrichments start to become noticeable. Such a threshold was found at 0.5% D, a surprisingly high value, while the ultralow deuterium concentrations (≤0.25% D) showed signs of the opposite trend. Bacterial adaptation for 400 generations in isotopically different environment confirmed preference for ultralow (≤0.25% D) enrichment. This effect appears to be similar to those described in sporadic but multiple earlier reports. Possible explanations include hormesis and isotopic resonance phenomena, with the latter explanation being favored. Public Library of Science 2014-07-17 /pmc/articles/PMC4102507/ /pubmed/25033078 http://dx.doi.org/10.1371/journal.pone.0102071 Text en © 2014 Xie, Zubarev http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Xie, Xueshu Zubarev, Roman A. Effects of Low-Level Deuterium Enrichment on Bacterial Growth |
title | Effects of Low-Level Deuterium Enrichment on Bacterial Growth |
title_full | Effects of Low-Level Deuterium Enrichment on Bacterial Growth |
title_fullStr | Effects of Low-Level Deuterium Enrichment on Bacterial Growth |
title_full_unstemmed | Effects of Low-Level Deuterium Enrichment on Bacterial Growth |
title_short | Effects of Low-Level Deuterium Enrichment on Bacterial Growth |
title_sort | effects of low-level deuterium enrichment on bacterial growth |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102507/ https://www.ncbi.nlm.nih.gov/pubmed/25033078 http://dx.doi.org/10.1371/journal.pone.0102071 |
work_keys_str_mv | AT xiexueshu effectsoflowleveldeuteriumenrichmentonbacterialgrowth AT zubarevromana effectsoflowleveldeuteriumenrichmentonbacterialgrowth |