Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues

Four-stranded G-quadruplex DNA secondary structures have recently been visualized in the nuclei of human cultured cells. Here, we show that BG4, a G-quadruplex-specific antibody, can be used to stain DNA G-quadruplex structures in patient-derived tissues using immunohistochemistry. We observe a sign...

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Detalles Bibliográficos
Autores principales: Biffi, Giulia, Tannahill, David, Miller, Jodi, Howat, William J., Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102534/
https://www.ncbi.nlm.nih.gov/pubmed/25033211
http://dx.doi.org/10.1371/journal.pone.0102711

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