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Targeted Inactivation of Cerberus Like-2 Leads to Left Ventricular Cardiac Hyperplasia and Systolic Dysfunction in the Mouse

Previous analysis of the Cerberus like 2 knockout (Cerl2(−/−)) mouse revealed a significant mortality during the first day after birth, mostly due to cardiac defects apparently associated with randomization of the left-right axis. We have however, identified Cerl2-associated cardiac defects, particu...

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Detalles Bibliográficos
Autores principales: Araújo, Ana Carolina, Marques, Sara, Belo, José António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102536/
https://www.ncbi.nlm.nih.gov/pubmed/25033293
http://dx.doi.org/10.1371/journal.pone.0102716