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Targeted Inactivation of Cerberus Like-2 Leads to Left Ventricular Cardiac Hyperplasia and Systolic Dysfunction in the Mouse
Previous analysis of the Cerberus like 2 knockout (Cerl2(−/−)) mouse revealed a significant mortality during the first day after birth, mostly due to cardiac defects apparently associated with randomization of the left-right axis. We have however, identified Cerl2-associated cardiac defects, particu...
Autores principales: | Araújo, Ana Carolina, Marques, Sara, Belo, José António |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102536/ https://www.ncbi.nlm.nih.gov/pubmed/25033293 http://dx.doi.org/10.1371/journal.pone.0102716 |
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