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HIV-1 Tropism Dynamics and Phylogenetic Analysis from Longitudinal Ultra-Deep Sequencing Data of CCR5- and CXCR4-Using Variants

OBJECTIVE: Coreceptor switch from CCR5 to CXCR4 is associated with HIV disease progression. The molecular and evolutionary mechanisms underlying the CCR5 to CXCR4 switch are the focus of intense recent research. We studied the HIV-1 tropism dynamics in relation to coreceptor usage, the nature of qua...

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Detalles Bibliográficos
Autores principales:	Sede, Mariano M., Moretti, Franco A., Laufer, Natalia L., Jones, Leandro R., Quarleri, Jorge F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102574/ https://www.ncbi.nlm.nih.gov/pubmed/25032817 http://dx.doi.org/10.1371/journal.pone.0102857

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