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β–Hydroxy β–Methylbutyrate Improves Dexamethasone-Induced Muscle Atrophy by Modulating the Muscle Degradation Pathway in SD Rat
Skeletal muscle atrophy results from various conditions including high levels of glucocorticoids, and β–hydroxy β–methylbutyrate (HMB; a metabolite of leucine) is a potent therapeutical supplement used to treat various muscle disorders. Recent studies have demonstrated that HMB inhibits dexamethason...
Autores principales: | Noh, Kyung Kyun, Chung, Ki Wung, Choi, Yeon Ja, Park, Min Hi, Jang, Eun Ji, Park, Chan Hum, Yoon, Changshin, Kim, Nam Deuk, Kim, Mi Kyung, Chung, Hae Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102592/ https://www.ncbi.nlm.nih.gov/pubmed/25032690 http://dx.doi.org/10.1371/journal.pone.0102947 |
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