Th2 cytokines increase Staphylococcus aureus alpha toxin induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6)

Atopic dermatitis (AD) is an inflammatory skin disease characterized by increased Th2 cytokine expression. AD skin lesions are often exacerbated by Staphylococcus aureus mediated secretion of the lytic virulence factor, alpha toxin. In the current study, we report that alpha toxin induced cell death...

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Detalles Bibliográficos
Autores principales: Brauweiler, Anne M, Goleva, Elena, Leung, Donald Y.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102636/
https://www.ncbi.nlm.nih.gov/pubmed/24468745
http://dx.doi.org/10.1038/jid.2014.43

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