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Vitamin D deficiency in women with polycystic ovary syndrome

OBJECTIVE: To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and the relationship between vitamin D status and clinical or metabolic features in this group. METHODS: We recruited 38 women with PCOS using the Rotterdam criteria. A total of 1...

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Autores principales: Kim, Jin Ju, Choi, Young Min, Chae, Soo Jin, Hwang, Kyu Ri, Yoon, Sang Ho, Kim, Min Jeong, Kim, Sun Mie, Ku, Seung Yup, Kim, Seok Hyun, Kim, Jung Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Reproductive Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102694/
https://www.ncbi.nlm.nih.gov/pubmed/25045632
http://dx.doi.org/10.5653/cerm.2014.41.2.80
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author Kim, Jin Ju
Choi, Young Min
Chae, Soo Jin
Hwang, Kyu Ri
Yoon, Sang Ho
Kim, Min Jeong
Kim, Sun Mie
Ku, Seung Yup
Kim, Seok Hyun
Kim, Jung Gu
author_facet Kim, Jin Ju
Choi, Young Min
Chae, Soo Jin
Hwang, Kyu Ri
Yoon, Sang Ho
Kim, Min Jeong
Kim, Sun Mie
Ku, Seung Yup
Kim, Seok Hyun
Kim, Jung Gu
author_sort Kim, Jin Ju
collection PubMed
description OBJECTIVE: To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and the relationship between vitamin D status and clinical or metabolic features in this group. METHODS: We recruited 38 women with PCOS using the Rotterdam criteria. A total of 109 premenopausal control women were matched with patients based on age and body mass index. Serum 25-hydroxy vitamin D concentrations less than 20 ng/mL were classified as frank vitamin D deficiency. Since vitamin D may play a significant role in metabolic disturbances in women with PCOS, correlations between clinical or metabolic parameters and vitamin D status were analyzed separately in patients and controls. RESULTS: Women with PCOS showed no differences in the level of 25-hydroxy vitamin D (19.6±6.6 ng/mL in patients vs. 20.1±7.4 ng/mL in controls, respectively, p=0.696) or prevalence of vitamin D deficiency (57.9% in patients vs. 56.5% in controls, respectively, p=0.880). In addition, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles in either PCOS patients or controls. CONCLUSION: Our study found no differences in the absolute level of serum vitamin D between PCOS patients and matched controls. Prevalence of vitamin D deficiency was equally common among both patients and controls. Additionally, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles, suggesting that the role of vitamin D in the pathogenesis of PCOS is not yet clear.
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spelling pubmed-41026942014-07-18 Vitamin D deficiency in women with polycystic ovary syndrome Kim, Jin Ju Choi, Young Min Chae, Soo Jin Hwang, Kyu Ri Yoon, Sang Ho Kim, Min Jeong Kim, Sun Mie Ku, Seung Yup Kim, Seok Hyun Kim, Jung Gu Clin Exp Reprod Med Original Article OBJECTIVE: To investigate: the prevalence of vitamin D deficiency in Korean women with polycystic ovary syndrome (PCOS), and the relationship between vitamin D status and clinical or metabolic features in this group. METHODS: We recruited 38 women with PCOS using the Rotterdam criteria. A total of 109 premenopausal control women were matched with patients based on age and body mass index. Serum 25-hydroxy vitamin D concentrations less than 20 ng/mL were classified as frank vitamin D deficiency. Since vitamin D may play a significant role in metabolic disturbances in women with PCOS, correlations between clinical or metabolic parameters and vitamin D status were analyzed separately in patients and controls. RESULTS: Women with PCOS showed no differences in the level of 25-hydroxy vitamin D (19.6±6.6 ng/mL in patients vs. 20.1±7.4 ng/mL in controls, respectively, p=0.696) or prevalence of vitamin D deficiency (57.9% in patients vs. 56.5% in controls, respectively, p=0.880). In addition, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles in either PCOS patients or controls. CONCLUSION: Our study found no differences in the absolute level of serum vitamin D between PCOS patients and matched controls. Prevalence of vitamin D deficiency was equally common among both patients and controls. Additionally, we did not find any correlations between serum vitamin D level and clinical or metabolic profiles, suggesting that the role of vitamin D in the pathogenesis of PCOS is not yet clear. The Korean Society for Reproductive Medicine 2014-06 2014-06-30 /pmc/articles/PMC4102694/ /pubmed/25045632 http://dx.doi.org/10.5653/cerm.2014.41.2.80 Text en Copyright © 2014. The Korean Society for Reproductive Medicine http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Jin Ju
Choi, Young Min
Chae, Soo Jin
Hwang, Kyu Ri
Yoon, Sang Ho
Kim, Min Jeong
Kim, Sun Mie
Ku, Seung Yup
Kim, Seok Hyun
Kim, Jung Gu
Vitamin D deficiency in women with polycystic ovary syndrome
title Vitamin D deficiency in women with polycystic ovary syndrome
title_full Vitamin D deficiency in women with polycystic ovary syndrome
title_fullStr Vitamin D deficiency in women with polycystic ovary syndrome
title_full_unstemmed Vitamin D deficiency in women with polycystic ovary syndrome
title_short Vitamin D deficiency in women with polycystic ovary syndrome
title_sort vitamin d deficiency in women with polycystic ovary syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102694/
https://www.ncbi.nlm.nih.gov/pubmed/25045632
http://dx.doi.org/10.5653/cerm.2014.41.2.80
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