Cargando…

Platelet volume indices in patients with varicocele

OBJECTIVE: This study sought to evaluate platelet volume indices (mean platelet volume [MPV], platelet distribution width [PDW], and platelet large cell ratio [P-LCR]) in varicocele patients, and compare it with platelet volume parameters in healthy controls. METHODS: This cross-sectional study invo...

Descripción completa

Detalles Bibliográficos
Autores principales: Mahdavi-Zafarghandi, Reza, Shakiba, Behnam, Keramati, Mohammad Reza, Tavakkoli, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Reproductive Medicine 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102696/
https://www.ncbi.nlm.nih.gov/pubmed/25045634
http://dx.doi.org/10.5653/cerm.2014.41.2.92
_version_ 1782327048541306880
author Mahdavi-Zafarghandi, Reza
Shakiba, Behnam
Keramati, Mohammad Reza
Tavakkoli, Mahmoud
author_facet Mahdavi-Zafarghandi, Reza
Shakiba, Behnam
Keramati, Mohammad Reza
Tavakkoli, Mahmoud
author_sort Mahdavi-Zafarghandi, Reza
collection PubMed
description OBJECTIVE: This study sought to evaluate platelet volume indices (mean platelet volume [MPV], platelet distribution width [PDW], and platelet large cell ratio [P-LCR]) in varicocele patients, and compare it with platelet volume parameters in healthy controls. METHODS: This cross-sectional study involved 2 groups: group 1 included 51 varicocele subjects and group 2 consisted of 50 healthy control subjects of similar ages. Peripheral venous blood samples were collected with ethylenediaminetetraacetic acid-K2 anticoagulant between 8:30 AM and 10 AM following an overnight fast. Platelet volume parameters (MPV, PDW, and P-LCR) were measured in both groups within 2 hours of sampling. RESULTS: The mean PDW, MPV, and P-LCR were 13.9±2.5%, 10.1±1.3 fL, and 27.3±7.8% in varicocele patients, respectively, and were 12.6±2.4%, 9.3±1.1 fL, and 21.9±6.4% in the control group, respectively. The mean PDW, MPV, and P-LCR were significantly higher in the varicocele group than the control group. CONCLUSION: The results of the present study suggest that vascular components may play an important role in the pathophysiology of varicocele; therefore, there is a great need for prospective studies to confirm this relationship.
format Online
Article
Text
id pubmed-4102696
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher The Korean Society for Reproductive Medicine
record_format MEDLINE/PubMed
spelling pubmed-41026962014-07-18 Platelet volume indices in patients with varicocele Mahdavi-Zafarghandi, Reza Shakiba, Behnam Keramati, Mohammad Reza Tavakkoli, Mahmoud Clin Exp Reprod Med Original Article OBJECTIVE: This study sought to evaluate platelet volume indices (mean platelet volume [MPV], platelet distribution width [PDW], and platelet large cell ratio [P-LCR]) in varicocele patients, and compare it with platelet volume parameters in healthy controls. METHODS: This cross-sectional study involved 2 groups: group 1 included 51 varicocele subjects and group 2 consisted of 50 healthy control subjects of similar ages. Peripheral venous blood samples were collected with ethylenediaminetetraacetic acid-K2 anticoagulant between 8:30 AM and 10 AM following an overnight fast. Platelet volume parameters (MPV, PDW, and P-LCR) were measured in both groups within 2 hours of sampling. RESULTS: The mean PDW, MPV, and P-LCR were 13.9±2.5%, 10.1±1.3 fL, and 27.3±7.8% in varicocele patients, respectively, and were 12.6±2.4%, 9.3±1.1 fL, and 21.9±6.4% in the control group, respectively. The mean PDW, MPV, and P-LCR were significantly higher in the varicocele group than the control group. CONCLUSION: The results of the present study suggest that vascular components may play an important role in the pathophysiology of varicocele; therefore, there is a great need for prospective studies to confirm this relationship. The Korean Society for Reproductive Medicine 2014-06 2014-06-30 /pmc/articles/PMC4102696/ /pubmed/25045634 http://dx.doi.org/10.5653/cerm.2014.41.2.92 Text en Copyright © 2014. The Korean Society for Reproductive Medicine http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mahdavi-Zafarghandi, Reza
Shakiba, Behnam
Keramati, Mohammad Reza
Tavakkoli, Mahmoud
Platelet volume indices in patients with varicocele
title Platelet volume indices in patients with varicocele
title_full Platelet volume indices in patients with varicocele
title_fullStr Platelet volume indices in patients with varicocele
title_full_unstemmed Platelet volume indices in patients with varicocele
title_short Platelet volume indices in patients with varicocele
title_sort platelet volume indices in patients with varicocele
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102696/
https://www.ncbi.nlm.nih.gov/pubmed/25045634
http://dx.doi.org/10.5653/cerm.2014.41.2.92
work_keys_str_mv AT mahdavizafarghandireza plateletvolumeindicesinpatientswithvaricocele
AT shakibabehnam plateletvolumeindicesinpatientswithvaricocele
AT keramatimohammadreza plateletvolumeindicesinpatientswithvaricocele
AT tavakkolimahmoud plateletvolumeindicesinpatientswithvaricocele