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Whole genome and exome sequencing of monozygotic twins discordant for Crohn’s disease
BACKGROUND: Crohn’s disease (CD) is an inflammatory bowel disease caused by genetic and environmental factors. More than 160 susceptibility loci have been identified for IBD, yet a large part of the genetic variance remains unexplained. Recent studies have demonstrated genetic differences between mo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102722/ https://www.ncbi.nlm.nih.gov/pubmed/24996980 http://dx.doi.org/10.1186/1471-2164-15-564 |