Lineage of origin in rhabdomyosarcoma informs pharmacological response

Lineage or cell of origin of cancers is often unknown and thus is not a consideration in therapeutic approaches. Alveolar rhabdomyosarcoma (aRMS) is an aggressive childhood cancer for which the cell of origin remains debated. We used conditional genetic mouse models of aRMS to activate the pathognom...

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Detalles Bibliográficos
Autores principales: Abraham, Jinu, Nuñez-Álvarez, Yaiza, Hettmer, Simone, Carrió, Elvira, Chen, Hung-I Harry, Nishijo, Koichi, Huang, Elaine T., Prajapati, Suresh I., Walker, Robert L., Davis, Sean, Rebeles, Jennifer, Wiebush, Hunter, McCleish, Amanda T., Hampton, Sheila T., Bjornson, Christopher R.R., Brack, Andrew S., Wagers, Amy J., Rando, Thomas A., Capecchi, Mario R., Marini, Frank C., Ehler, Benjamin R., Zarzabal, Lee Ann, Goros, Martin W., Michalek, Joel E., Meltzer, Paul S., Langenau, David M., LeGallo, Robin D., Mansoor, Atiya, Chen, Yidong, Suelves, Mònica, Rubin, Brian P., Keller, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102765/
https://www.ncbi.nlm.nih.gov/pubmed/25030697
http://dx.doi.org/10.1101/gad.238733.114

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