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Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation
Aurora A and JAK2 kinases are involved in cell division and tumor cell survival, respectively. Here we demonstrate that ectopic expression of Aurora A and JAK2 together is more effective than each alone at inducing non-transformed cells to grow in an anchorage-independent manner and to invade. Furth...
Autores principales: | Yang, Hua, Lawrence, Harshani R., Kazi, Aslamuzzaman, Gevariya, Harsukh, Patel, Ronil, Luo, Yunting, Rix, Uwe, Schonbrunn, Ernst, Lawrence, Nicholas J., Sebti, Said M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102782/ https://www.ncbi.nlm.nih.gov/pubmed/24930769 |
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