Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production

Chromosomal band 11q13 seems to be one of the most frequently amplified lesions in human cancer, including esophageal squamous cell cancer (ESCC). The oral cancer overexpressed 1 (ORAOV1) gene has been identified within this region, but its detailed biological function in human ESCC remains largely...

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Detalles Bibliográficos
Autores principales: Togashi, Yosuke, Arao, Tokuzo, Kato, Hiroaki, Matsumoto, Kazuko, Terashima, Masato, Hayashi, Hidetoshi, de Velasco, Marco A, Fujita, Yoshihiko, Kimura, Hideharu, Yasuda, Takushi, Shiozaki, Hitoshi, Nishio, Kazuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102783/
https://www.ncbi.nlm.nih.gov/pubmed/24930674

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