Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity

Multiple myeloma (MM) cells induce relevant angiogenic effects within the human bone marrow milieu (huBMM) by the aberrant expression of angiogenic factors. Hypoxia triggers angiogenic events within the huBMM and the transcription factor hypoxia-inducible factor-1α (HIF-1α) is over-expressed by MM c...

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Detalles Bibliográficos
Autores principales: Raimondi, Lavinia, Amodio, Nicola, Di Martino, Maria Teresa, Altomare, Emanuela, Leotta, Marzia, Caracciolo, Daniele, Gullà, Annamaria, Neri, Antonino, Taverna, Simona, D'Aquila, Patrizia, Alessandro, Riccardo, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102790/
https://www.ncbi.nlm.nih.gov/pubmed/24839982

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