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Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis
The Notch ligand Delta-like 4 (DLL4) plays an important role in tumor angiogenesis, which is required for tumor invasion and metastasis. Here we showed that DLL4 was elevated in endothelium and Notch signaling was activated in renal cell carcinoma (RCC). Exogenous DLL4 induced RCC cell migration and...
Autores principales: | Huang, Qing Bo, Ma, Xin, Li, Hong Zhao, Ai, Qing, Liu, Shang Wen, Zhang, Yu, Gao, Yu, Fan, Yang, Ni, Dong, Wang, Bao Jun, Zhang, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102792/ https://www.ncbi.nlm.nih.gov/pubmed/24931473 |
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