Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs

HIP-55 (HPK1-interacting protein of 55 kDa, also named DBNL, SH3P7, and mAbp1) is a multidomain adaptor protein that is critical for organ development and the immune response. Here, we report the coupling of HIP-55 to cell growth control through its 14-3-3-binding phospho-Ser/Thr-sensor sites. Using...

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Detalles Bibliográficos
Autores principales: Li, Zijian, Park, Hae Ryon, Shi, Zhi, Li, Zenggang, Pham, Cau Dinh, Du, Yuhong, Khuri, Fadlo R., Zhang, Youyi, Han, Qide, Fu, Haian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102803/
https://www.ncbi.nlm.nih.gov/pubmed/24912570

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