The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors

Rhabdoid sarcomas are highly malignant tumors that usually occur in young children. A key to the genesis of this tumor is the mutational loss of the BAF47 gene as well as the widespread epigenetic suppression of other key anticancer genes. The BRM gene is one such epigenetically silenced gene in Rha...

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Detalles Bibliográficos
Autores principales: Kahali, Bhaskar, Yu, Jinlong, Marquez, Stefanie B., Thompson, Kenneth. W., Liang, Shermi Y., Lu, Li, Reisman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102812/
https://www.ncbi.nlm.nih.gov/pubmed/24913006

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