ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents

Microtubule-targeting agents (MTAs) are largely administered in adults and children cancers. Better deciphering their mechanism of action is of prime importance to develop more convenient therapy strategies. Here, we addressed the question of how reactive oxygen species (ROS) generation by mitochond...

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Detalles Bibliográficos
Autores principales: Grand, Marion Le, Rovini, Amandine, Bourgarel-Rey, Veronique, Honore, Stephane, Bastonero, Sonia, Braguer, Diane, Carre, Manon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102819/
https://www.ncbi.nlm.nih.gov/pubmed/24930764

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