Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB

Growing evidence links tumor progression with chronic inflammatory processes and dysregulated activity of various immune cells. In this study, we demonstrate that various types of macrophages internalize microvesicles, called exosomes, secreted by breast cancer and non-cancerous cell lines. Although...

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Detalles Bibliográficos
Autores principales: Chow, Amy, Zhou, Weiying, Liu, Liang, Fong, Miranda Y., Champer, Jackson, Van Haute, Desiree, Chin, Andrew R., Ren, Xiubao, Gugiu, Bogdan Gabriel, Meng, Zhipeng, Huang, Wendong, Ngo, Vu, Kortylewski, Marcin, Wang, Shizhen Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102923/
https://www.ncbi.nlm.nih.gov/pubmed/25034888
http://dx.doi.org/10.1038/srep05750

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