MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G(1)/S transition and apoptosis by targeting p21(WAF1/CIP1)

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BACKGROUND: Increasing evidence has shown that microRNAs (miRNAs) can serve as oncogenes and tumour suppressors to participate in tumour development. However, the roles of miRNAs in chemoresistance of human lung adenocarcinoma (LA) remain largely undefined. METHODS: On the basis of miRNA microarray...

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Detalles Bibliográficos
Autores principales: Wang, H, Zhu, L-J, Yang, Y-C, Wang, Z-X, Wang, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102932/
https://www.ncbi.nlm.nih.gov/pubmed/24921914
http://dx.doi.org/10.1038/bjc.2014.157

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