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Dichloroacetate induces autophagy in colorectal cancer cells and tumours

BACKGROUND: Dichloroacetate (DCA) has been found to have antitumour properties. METHODS: We investigated the cellular and metabolic responses to DCA treatment and recovery in human colorectal (HT29, HCT116 WT and HCT116 Bax-ko), prostate carcinoma cells (PC3) and HT29 xenografts by flow cytometry, w...

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Detalles Bibliográficos
Autores principales:	Lin, G, Hill, D K, Andrejeva, G, Boult, J K R, Troy, H, Fong, A-C L F W T, Orton, M R, Panek, R, Parkes, H G, Jafar, M, Koh, D-M, Robinson, S P, Judson, I R, Griffiths, J R, Leach, M O, Eykyn, T R, Chung, Y-L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102941/ https://www.ncbi.nlm.nih.gov/pubmed/24892448 http://dx.doi.org/10.1038/bjc.2014.281

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