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T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma

Cutaneous pseudolymphomas refer to a group of benign reactive T or B cell lymphoproliferative processes that simulate cutaneous lymphomas. T cell rich angiomatoid polypoid pseudo lymphoma (TRAPP) of the skin is a unique form of T cell rich cutaneous pseudolymphoma. A 13-year-girl presented with an a...

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Autores principales: Sandhya, V, Jayaraman, Alamelu, Srinivas, CR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103272/
https://www.ncbi.nlm.nih.gov/pubmed/25071255
http://dx.doi.org/10.4103/0019-5154.135486
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author Sandhya, V
Jayaraman, Alamelu
Srinivas, CR
author_facet Sandhya, V
Jayaraman, Alamelu
Srinivas, CR
author_sort Sandhya, V
collection PubMed
description Cutaneous pseudolymphomas refer to a group of benign reactive T or B cell lymphoproliferative processes that simulate cutaneous lymphomas. T cell rich angiomatoid polypoid pseudo lymphoma (TRAPP) of the skin is a unique form of T cell rich cutaneous pseudolymphoma. A 13-year-girl presented with an asymptomatic skin colored papule on the right elbow, the biopsy of which revealed features consistent with TRAPP. The dermis showed an infiltrate of lymphocytes, plasma cells, and histiocytes along with prominent vascular channels lined by plump endothelium. An immunohistochemical study showed a predominance of T cells over B cells. The morphological and immunohistochemical features pointed towards the diagnosis of TRAPP. We report this rare entity, only 17 cases of which have been described so far in literature. The differential diagnoses have also been discussed.
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spelling pubmed-41032722014-07-28 T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma Sandhya, V Jayaraman, Alamelu Srinivas, CR Indian J Dermatol Dermatopathology Round Cutaneous pseudolymphomas refer to a group of benign reactive T or B cell lymphoproliferative processes that simulate cutaneous lymphomas. T cell rich angiomatoid polypoid pseudo lymphoma (TRAPP) of the skin is a unique form of T cell rich cutaneous pseudolymphoma. A 13-year-girl presented with an asymptomatic skin colored papule on the right elbow, the biopsy of which revealed features consistent with TRAPP. The dermis showed an infiltrate of lymphocytes, plasma cells, and histiocytes along with prominent vascular channels lined by plump endothelium. An immunohistochemical study showed a predominance of T cells over B cells. The morphological and immunohistochemical features pointed towards the diagnosis of TRAPP. We report this rare entity, only 17 cases of which have been described so far in literature. The differential diagnoses have also been discussed. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4103272/ /pubmed/25071255 http://dx.doi.org/10.4103/0019-5154.135486 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Dermatopathology Round
Sandhya, V
Jayaraman, Alamelu
Srinivas, CR
T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma
title T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma
title_full T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma
title_fullStr T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma
title_full_unstemmed T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma
title_short T-Cell Rich Angiomatoid Polypoid Pseudolymphoma: A Novel Cutaneous Pseudolymphoma
title_sort t-cell rich angiomatoid polypoid pseudolymphoma: a novel cutaneous pseudolymphoma
topic Dermatopathology Round
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103272/
https://www.ncbi.nlm.nih.gov/pubmed/25071255
http://dx.doi.org/10.4103/0019-5154.135486
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