MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms

Despite the growing number of genome-wide association studies, the involvement of polymorphisms in microRNA target sites (polymiRTS) in Alzheimer’s disease (AD) remains poorly investigated. Recently, we have shown that AD-associated single-nucleotide polymorphisms (SNPs) present in the 3′ untranslat...

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Detalles Bibliográficos
Autores principales: Delay, Charlotte, Dorval, Véronique, Fok, Alice, Grenier-Boley, Benjamin, Lambert, Jean-Charles, Hsiung, G.-Y., Hébert, Sébastien S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103510/
https://www.ncbi.nlm.nih.gov/pubmed/25100943
http://dx.doi.org/10.3389/fnmol.2014.00067

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