Generation and Characterization of a JAK2V617F-Containing Erythroleukemia Cell Line

The JAK2V617F mutation is found in the majority of patients with myeloproliferative neoplasms (MPNs). Transgenic expression of the mutant gene causes MPN-like phenotypes in mice. We have produced JAK2V617F mice with p53 null background. Some of these mice developed acute erythroleukemia. From one of...

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Detalles Bibliográficos
Autores principales: Zhao, Wanke, Zou, Kang, Farasyn, Taleah, Ho, Wanting Tina, Zhao, Zhizhuang Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103785/
https://www.ncbi.nlm.nih.gov/pubmed/25036984
http://dx.doi.org/10.1371/journal.pone.0099017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103785/
https://www.ncbi.nlm.nih.gov/pubmed/25036984
http://dx.doi.org/10.1371/journal.pone.0099017

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