Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery

One of the greatest challenges in biomedical research, drug discovery and diagnostics is understanding how seemingly identical cells can respond differently to perturbagens including drugs for disease treatment. Although heterogeneity has become an accepted characteristic of a population of cells, i...

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Detalles Bibliográficos
Autores principales: Gough, Albert H., Chen, Ning, Shun, Tong Ying, Lezon, Timothy R., Boltz, Robert C., Reese, Celeste E., Wagner, Jacob, Vernetti, Lawrence A., Grandis, Jennifer R., Lee, Adrian V., Stern, Andrew M., Schurdak, Mark E., Taylor, D. Lansing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103836/
https://www.ncbi.nlm.nih.gov/pubmed/25036749
http://dx.doi.org/10.1371/journal.pone.0102678

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