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Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1
Dynamin-Related Protein 1 (Drp1), a large GTPase of the dynamin superfamily, is required for mitochondrial fission in healthy and apoptotic cells. Drp1 activation is a complex process that involves translocation from the cytosol to the mitochondrial outer membrane (MOM) and assembly into rings/spira...
Autores principales: | Bustillo-Zabalbeitia, Itsasne, Montessuit, Sylvie, Raemy, Etienne, Basañez, Gorka, Terrones, Oihana, Martinou, Jean-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103857/ https://www.ncbi.nlm.nih.gov/pubmed/25036098 http://dx.doi.org/10.1371/journal.pone.0102738 |
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