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Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1

Dynamin-Related Protein 1 (Drp1), a large GTPase of the dynamin superfamily, is required for mitochondrial fission in healthy and apoptotic cells. Drp1 activation is a complex process that involves translocation from the cytosol to the mitochondrial outer membrane (MOM) and assembly into rings/spira...

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Detalles Bibliográficos
Autores principales: Bustillo-Zabalbeitia, Itsasne, Montessuit, Sylvie, Raemy, Etienne, Basañez, Gorka, Terrones, Oihana, Martinou, Jean-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103857/
https://www.ncbi.nlm.nih.gov/pubmed/25036098
http://dx.doi.org/10.1371/journal.pone.0102738

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