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A Meta-Analysis Approach for Characterizing Pan-Cancer Mechanisms of Drug Sensitivity in Cell Lines

Understanding the heterogeneous drug response of cancer patients is essential to precision oncology. Pioneering genomic analyses of individual cancer subtypes have begun to identify key determinants of resistance, including up-regulation of multi-drug resistance (MDR) genes and mutational alteration...

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Detalles Bibliográficos
Autores principales:	Wang, Kendric, Shrestha, Raunak, Wyatt, Alexander W., Reddy, Anupama, Lehár, Joseph, Wang, Yuzhou, Lapuk, Anna, Collins, Colin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103868/ https://www.ncbi.nlm.nih.gov/pubmed/25036042 http://dx.doi.org/10.1371/journal.pone.0103050

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