Oxaliplatin Neurotoxicity Involves Peroxisome Alterations. PPARγ Agonism as Preventive Pharmacological Approach

The development of neuropathic syndromes is an important, dose limiting side effect of anticancer agents like platinum derivates, taxanes and vinca alkaloids. The causes of neurotoxicity are still unclear but the impairment of the oxidative equilibrium is strictly related to pain. Two intracellular...

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Detalles Bibliográficos
Autores principales: Zanardelli, Matteo, Micheli, Laura, Cinci, Lorenzo, Failli, Paola, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103888/
https://www.ncbi.nlm.nih.gov/pubmed/25036594
http://dx.doi.org/10.1371/journal.pone.0102758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103888/
https://www.ncbi.nlm.nih.gov/pubmed/25036594
http://dx.doi.org/10.1371/journal.pone.0102758

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