MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

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Foxp3(+) T regulatory (Treg) cells prevent inflammatory disease but the mechanistic basis of suppression is not understood completely. Gene silencing by RNA interference can act in a cell-autonomous and non-cell-autonomous manner, providing mechanisms of intercellular regulation. Here, we demonstrat...

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Detalles Bibliográficos
Autores principales: Okoye, Isobel S., Coomes, Stephanie M., Pelly, Victoria S., Czieso, Stephanie, Papayannopoulos, Venizelos, Tolmachova, Tanya, Seabra, Miguel C., Wilson, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104030/
https://www.ncbi.nlm.nih.gov/pubmed/25035954
http://dx.doi.org/10.1016/j.immuni.2014.05.019
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