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New developments in the treatment of castration resistant prostate cancer
In the past 5 years, the treatment and understanding of metastatic castrate resistant prostate cancer (CRPC) have improved dramatically. Our understanding of the mechanisms of castration resistance has allowed for the development of new drugs to target prostate cancer, and our understanding of genet...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104080/ https://www.ncbi.nlm.nih.gov/pubmed/24759588 http://dx.doi.org/10.4103/1008-682X.127824 |
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author | Wadia, Roxanne Petrylak, Daniel P |
author_facet | Wadia, Roxanne Petrylak, Daniel P |
author_sort | Wadia, Roxanne |
collection | PubMed |
description | In the past 5 years, the treatment and understanding of metastatic castrate resistant prostate cancer (CRPC) have improved dramatically. Our understanding of the mechanisms of castration resistance has allowed for the development of new drugs to target prostate cancer, and our understanding of genetic mutations may give us new tools with which to more accurately diagnose and be able to predict the course of this heterogeneous disease. This article summarizes the recent advances in the understanding of the development of CRPC, as well as the new drugs and targets, which have evolved from this basic research. |
format | Online Article Text |
id | pubmed-4104080 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41040802014-07-29 New developments in the treatment of castration resistant prostate cancer Wadia, Roxanne Petrylak, Daniel P Asian J Androl Invited Review In the past 5 years, the treatment and understanding of metastatic castrate resistant prostate cancer (CRPC) have improved dramatically. Our understanding of the mechanisms of castration resistance has allowed for the development of new drugs to target prostate cancer, and our understanding of genetic mutations may give us new tools with which to more accurately diagnose and be able to predict the course of this heterogeneous disease. This article summarizes the recent advances in the understanding of the development of CRPC, as well as the new drugs and targets, which have evolved from this basic research. Medknow Publications & Media Pvt Ltd 2014 2014-04-08 /pmc/articles/PMC4104080/ /pubmed/24759588 http://dx.doi.org/10.4103/1008-682X.127824 Text en Copyright: © Asian Journal of Andrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Invited Review Wadia, Roxanne Petrylak, Daniel P New developments in the treatment of castration resistant prostate cancer |
title | New developments in the treatment of castration resistant prostate cancer |
title_full | New developments in the treatment of castration resistant prostate cancer |
title_fullStr | New developments in the treatment of castration resistant prostate cancer |
title_full_unstemmed | New developments in the treatment of castration resistant prostate cancer |
title_short | New developments in the treatment of castration resistant prostate cancer |
title_sort | new developments in the treatment of castration resistant prostate cancer |
topic | Invited Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104080/ https://www.ncbi.nlm.nih.gov/pubmed/24759588 http://dx.doi.org/10.4103/1008-682X.127824 |
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