Management of localized prostate cancer: the pendulum swings (back to the middle)

Herein, we discuss 18-year follow-up data from the Scandinavian Prostate Cancer Group-4 (SPCG-4) trial, a randomized study comparing observation and radical prostatectomy (RP) in patients with localized prostate cancer. The results of this study are contrasted with another study employing a similar...

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Detalles Bibliográficos
Autores principales: Vuong, Winston, Sartor, Oliver, Pal, Sumanta K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Invited Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104085/
https://www.ncbi.nlm.nih.gov/pubmed/24875822
http://dx.doi.org/10.4103/1008-682X.131072
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author Vuong, Winston
Sartor, Oliver
Pal, Sumanta K
author_facet Vuong, Winston
Sartor, Oliver
Pal, Sumanta K
author_sort Vuong, Winston
collection PubMed
description Herein, we discuss 18-year follow-up data from the Scandinavian Prostate Cancer Group-4 (SPCG-4) trial, a randomized study comparing observation and radical prostatectomy (RP) in patients with localized prostate cancer. The results of this study are contrasted with another study employing a similar randomization, the Prostate Cancer Intervention Versus Observation Trial (PIVOT). We highlight several key differences in study eligibility and enrollment that may account for distinct results, and describe how these datasets impact the complex landscape of therapy for localized prostate cancer.
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spelling pubmed-41040852014-07-29 Management of localized prostate cancer: the pendulum swings (back to the middle) Vuong, Winston Sartor, Oliver Pal, Sumanta K Asian J Androl Invited Research Highlight Herein, we discuss 18-year follow-up data from the Scandinavian Prostate Cancer Group-4 (SPCG-4) trial, a randomized study comparing observation and radical prostatectomy (RP) in patients with localized prostate cancer. The results of this study are contrasted with another study employing a similar randomization, the Prostate Cancer Intervention Versus Observation Trial (PIVOT). We highlight several key differences in study eligibility and enrollment that may account for distinct results, and describe how these datasets impact the complex landscape of therapy for localized prostate cancer. Medknow Publications & Media Pvt Ltd 2014 2014-05-23 /pmc/articles/PMC4104085/ /pubmed/24875822 http://dx.doi.org/10.4103/1008-682X.131072 Text en Copyright: © Asian Journal of Andrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Invited Research Highlight
Vuong, Winston
Sartor, Oliver
Pal, Sumanta K
Management of localized prostate cancer: the pendulum swings (back to the middle)
title Management of localized prostate cancer: the pendulum swings (back to the middle)
title_full Management of localized prostate cancer: the pendulum swings (back to the middle)
title_fullStr Management of localized prostate cancer: the pendulum swings (back to the middle)
title_full_unstemmed Management of localized prostate cancer: the pendulum swings (back to the middle)
title_short Management of localized prostate cancer: the pendulum swings (back to the middle)
title_sort management of localized prostate cancer: the pendulum swings (back to the middle)
topic Invited Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104085/
https://www.ncbi.nlm.nih.gov/pubmed/24875822
http://dx.doi.org/10.4103/1008-682X.131072
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