Cargando…
Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells
Cell populations can be strikingly heterogeneous, composed of multiple cellular states, each exhibiting stochastic noise in its gene expression. A major challenge is to disentangle these two types of variability and to understand the dynamic processes and mechanisms that control them. Embryonic stem...
Autores principales: | Singer, Zakary S., Yong, John, Tischler, Julia, Hackett, Jamie A., Altinok, Alphan, Surani, M. Azim, Cai, Long, Elowitz, Michael B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104113/ https://www.ncbi.nlm.nih.gov/pubmed/25038413 http://dx.doi.org/10.1016/j.molcel.2014.06.029 |
Ejemplares similares
-
Tracing the Derivation of Embryonic Stem Cells from the Inner Cell Mass by Single-Cell RNA-Seq Analysis
por: Tang, Fuchou, et al.
Publicado: (2010) -
DNA methylation dynamics during the mammalian life cycle
por: Hackett, Jamie A., et al.
Publicado: (2013) -
DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation
por: Farlik, Matthias, et al.
Publicado: (2016) -
Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation
por: Grabole, Nils, et al.
Publicado: (2013) -
A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development
por: Tang, Walfred W.C., et al.
Publicado: (2015)