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A G-Quadruplex-Containing RNA Activates Fluorescence in a GFP-Like Fluorophore
Spinach is an in vitro selected RNA aptamer that binds a GFP-like ligand and activates its green fluorescence.Spinach is thus an RNA analog of GFP, and has potentially widespread applications for in vivo labeling and imaging. We used antibody-assisted crystallography to determine the structures of S...
Autores principales: | Huang, Hao, Suslov, Nikolai B., Li, Nan-Sheng, Shelke, Sandip A., Evans, Molly E., Koldobskaya, Yelena, Rice, Phoebe A., Piccirilli, Joseph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104137/ https://www.ncbi.nlm.nih.gov/pubmed/24952597 http://dx.doi.org/10.1038/nchembio.1561 |
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