Cargando…

Estradiol Binds to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro

Rationale: Insulin (INS) resistance associated with hyperestrogenemias occurs in gestational diabetes mellitus, polycystic ovary syndrome, ovarian hyperstimulation syndrome, estrogen therapies, metabolic syndrome, and obesity. The mechanism by which INS and estrogen interact is unknown. We hypothesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Root-Bernstein, Robert, Podufaly, Abigail, Dillon, Patrick F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104309/ https://www.ncbi.nlm.nih.gov/pubmed/25101056 http://dx.doi.org/10.3389/fendo.2014.00118

Ejemplares similares

Rapid Non-Enzymatic Glycation of the Insulin Receptor under Hyperglycemic Conditions Inhibits Insulin Binding In Vitro: Implications for Insulin Resistance
por: Rhinesmith, Tyler, et al.
Publicado: (2017)

Uric Acid Impairs Insulin Signaling by Promoting Enpp1 Binding to Insulin Receptor in Human Umbilical Vein Endothelial Cells
por: Tassone, Eliezer J., et al.
Publicado: (2018)

Insulin-Like Growth Factor Binding Proteins in Autoimmune Diseases
por: Ding, Huihua, et al.
Publicado: (2018)

Insulin-Like Growth Factor-Binding Proteins of Teleost Fishes
por: Garcia de la Serrana, Daniel, et al.
Publicado: (2018)

Structural Perspectives of Insulin Receptor Isoform-Selective Insulin Analogs
por: Jiráček, Jiří, et al.
Publicado: (2017)

Insulin-Like Growth Factor Binding Proteins: A Structural Perspective
por: Forbes, Briony E., et al.
Publicado: (2012)

Insulin-Like Growth Factor Binding Protein-5 in Physiology and Disease
por: Duan, Cunming, et al.
Publicado: (2020)

Corrigendum: Insulin-Like Growth Factor Binding Protein-5 in Physiology and Disease
por: Duan, Cunming, et al.
Publicado: (2020)

Cross-Linking/Mass Spectrometry Uncovers Details of Insulin-Like Growth Factor Interaction With Insect Insulin Binding Protein Imp-L2
por: Pompach, Petr, et al.
Publicado: (2019)

Editorial: Current Perspectives on Insulin-Like Growth Factor Binding Protein (IGFBP) Research
por: Hoeflich, Andreas, et al.
Publicado: (2018)

Far-western Blotting Detection of the Binding of Insulin Receptor Substrate to the Insulin Receptor
por: Peng, Jinghua, et al.
Publicado: (2023)

Ligand-Mediated Endocytosis and Trafficking of the Insulin-Like Growth Factor Receptor I and Insulin Receptor Modulate Receptor Function
por: Morcavallo, Alaide, et al.
Publicado: (2014)

Identification of Host Insulin Binding Sites on Schistosoma japonicum Insulin Receptors
por: Stephenson, Rachel J., et al.
Publicado: (2016)

Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function
por: Tatar, Marc
Publicado: (2021)

IGF-I, IGF-II, and Insulin Stimulate Different Gene Expression Responses through Binding to the IGF-I Receptor
por: Versteyhe, Soetkin, et al.
Publicado: (2013)

The role of peripheral β-amyloid in insulin resistance, insulin secretion, and prediabetes: in vitro and population-based studies
por: Xu, Zihui, et al.
Publicado: (2023)

Chromium–Insulin Reduces Insulin Clearance and Enhances Insulin Signaling by Suppressing Hepatic Insulin-Degrading Enzyme and Proteasome Protein Expression in KKAy Mice
por: Wang, Zhong Q., et al.
Publicado: (2014)

Abnormality of insulin binding and receptor phosphorylation in an insulin-resistant melanoma cell line
Publicado: (1984)

Effects of Transport Duration and Environmental Conditions in Winter or Summer on the Concentrations of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Plasma of Market-Weight Pigs
por: Wirthgen, Elisa, et al.
Publicado: (2018)

Differential Effects of Camel Milk on Insulin Receptor Signaling – Toward Understanding the Insulin-Like Properties of Camel Milk
por: Abdulrahman, Abdulrasheed O., et al.
Publicado: (2016)

All-Atom Structural Models of the Transmembrane Domains of Insulin and Type 1 Insulin-Like Growth Factor Receptors
por: Mohammadiarani, Hossein, et al.
Publicado: (2016)

Secretagogin Regulates Insulin Signaling by Direct Insulin Binding
por: Sharma, Anand Kumar, et al.
Publicado: (2019)

The Evolving Importance of Insulin Signaling in Podocyte Health and Disease
por: Lay, Abigail C., et al.
Publicado: (2018)

Landmarks in Insulin Research
por: Ward, Colin W., et al.
Publicado: (2011)

Insulin Signaling and Autism
por: Stern, Michael
Publicado: (2011)

Conformational Dynamics of Insulin
por: Hua, Qing-Xin, et al.
Publicado: (2011)

Insulin Analogs and Cancer
por: Sciacca, Laura, et al.
Publicado: (2012)

Sirtuins and Insulin Resistance
por: Zhou, Shuang, et al.
Publicado: (2018)

Insulin Resistance in Children
por: Tagi, Veronica Maria, et al.
Publicado: (2019)

Editorial: Insulin and The Brain
por: Taouis, Mohammed, et al.
Publicado: (2019)

The Insulin Receptor: A New Target for Cancer Therapy
por: Malaguarnera, Roberta, et al.
Publicado: (2011)

Insulin Receptor Isoform Variations in Prostate Cancer Cells
por: Perks, Claire M., et al.
Publicado: (2016)

Regulation of the immune system by the insulin receptor in health and disease
por: Makhijani, Priya, et al.
Publicado: (2023)

Heparin impairs skeletal muscle glucose uptake by inhibiting insulin binding to insulin receptor
por: Zhu, Canjun, et al.
Publicado: (2021)

Insulin Sensitivity Is Not Decreased in Adult Patients With Hypopituitarism Without Growth Hormone Replacement
por: Castillo, Alejandro Rosell, et al.
Publicado: (2019)

Ligand-Binding Affinity at the Insulin Receptor Isoform-A and Subsequent IR-A Tyrosine Phosphorylation Kinetics are Important Determinants of Mitogenic Biological Outcomes
por: Rajapaksha, Harinda, et al.
Publicado: (2015)

Insulin-Like Growth Factor Binding Proteins and IGFBP Proteases: A Dynamic System Regulating the Ovarian Folliculogenesis
por: Mazerbourg, Sabine, et al.
Publicado: (2018)

Lipid droplet accumulation in β cells in patients with type 2 diabetes is associated with insulin resistance, hyperglycemia and β cell dysfunction involving decreased insulin granules
por: Horii, Tomomi, et al.
Publicado: (2022)

APPL1 Potentiates Insulin Sensitivity by Facilitating the Binding of IRS1/2 to the Insulin Receptor
por: Ryu, Jiyoon, et al.
Publicado: (2014)

The Emerging Role of Insulin and Insulin-Like Growth Factor Signaling in Cancer Stem Cells
por: Malaguarnera, Roberta, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_c9fphg5hkof6tf8e82e47ba5dl