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Impact of residues remote from the catalytic centre on enzyme catalysis of copper nitrite reductase
Enzyme mechanisms are often probed by structure-informed point mutations and measurement of their effects on enzymatic properties to test mechanistic hypotheses. In many cases, the challenge is to report on complex, often inter-linked elements of catalysis. Evidence for long-range effects on enzyme...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104443/ https://www.ncbi.nlm.nih.gov/pubmed/25022223 http://dx.doi.org/10.1038/ncomms5395 |