Cargando…

Quantitative flux analysis reveals folate-dependent NADPH production

ATP is the dominant energy source in animals for mechanical and electrical work (e.g., muscle contraction, neuronal firing). For chemical work, there is an equally important role for NADPH, which powers redox defense and reductive biosynthesis(1). The most direct route to produce NADPH from glucose...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Jing, Ye, Jiangbin, Kamphorst, Jurre J., Shlomi, Tomer, Thompson, Craig B., Rabinowitz, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104482/
https://www.ncbi.nlm.nih.gov/pubmed/24805240
http://dx.doi.org/10.1038/nature13236