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A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects
The switch to a modern lifestyle in recent decades has coincided with a rapid increase in prevalence of obesity and other diseases. These shifts in prevalence could be explained by the release of genetic susceptibility for disease in the form of gene-by-environment (GxE) interactions. Yet, the detec...
Autores principales: | Marigorta, Urko M., Gibson, Greg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104702/ https://www.ncbi.nlm.nih.gov/pubmed/25101110 http://dx.doi.org/10.3389/fgene.2014.00225 |
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