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Inferring multi-target QSAR models with taxonomy-based multi-task learning

BACKGROUND: A plethora of studies indicate that the development of multi-target drugs is beneficial for complex diseases like cancer. Accurate QSAR models for each of the desired targets assist the optimization of a lead candidate by the prediction of affinity profiles. Often, the targets of a multi...

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Detalles Bibliográficos
Autores principales:	Rosenbaum, Lars, Dörr, Alexander, Bauer, Matthias R, Boeckler, Frank M, Zell, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104930/ https://www.ncbi.nlm.nih.gov/pubmed/23842210 http://dx.doi.org/10.1186/1758-2946-5-33

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