AN UPWARD TREND IN DNA P16INK4A METHYLATION PATTERN AND HIGH RISK HPV INFECTION ACCORDING TO THE SEVERITY OF THE CERVICAL LESION

High-risk human papillomavirus (hr-HPV) infection is necessary but not sufficient for cervical cancer development. Recently, P16INK4A gene silencing through hypermethylation has been proposed as an important cofactor in cervical carcinogenesis due to its tumor suppressor function. We aimed to invest...

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Detalles Bibliográficos
Autores principales: Carestiato, Fernanda Nahoum, Afonso, Larissa Alves, Moysés, Natalia, Almeida, Gutemberg Leão, Velarde, Luis Guillermo Coca, Cavalcanti, Silvia Maria Baeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2013
Materias:
HPV
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105070/
https://www.ncbi.nlm.nih.gov/pubmed/24037287
http://dx.doi.org/10.1590/S0036-46652013000500006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105070/
https://www.ncbi.nlm.nih.gov/pubmed/24037287
http://dx.doi.org/10.1590/S0036-46652013000500006

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