PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE

In a previous study our group found that the probiotic Saccharomyces boulardii was capable of reducing the intensity of infection in mice with toxocariasis. In order to assess whether the mechanism involved would be a direct action of the probiotic on Toxocara canis larvae, this study was designed....

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Autores principales: de Avila, Luciana Farias da Costa, Telmo, Paula de Lima, Martins, Lourdes Helena Rodrigues, Glaeser, Thaís Aimeé, Conceição, Fabricio Rochedo, Leite, Fábio Pereira Leivas, Scaini, Carlos James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2013
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105076/
https://www.ncbi.nlm.nih.gov/pubmed/24037293
http://dx.doi.org/10.1590/S0036-46652013000500012
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author de Avila, Luciana Farias da Costa
Telmo, Paula de Lima
Martins, Lourdes Helena Rodrigues
Glaeser, Thaís Aimeé
Conceição, Fabricio Rochedo
Leite, Fábio Pereira Leivas
Scaini, Carlos James
author_facet de Avila, Luciana Farias da Costa
Telmo, Paula de Lima
Martins, Lourdes Helena Rodrigues
Glaeser, Thaís Aimeé
Conceição, Fabricio Rochedo
Leite, Fábio Pereira Leivas
Scaini, Carlos James
author_sort de Avila, Luciana Farias da Costa
collection PubMed
description In a previous study our group found that the probiotic Saccharomyces boulardii was capable of reducing the intensity of infection in mice with toxocariasis. In order to assess whether the mechanism involved would be a direct action of the probiotic on Toxocara canis larvae, this study was designed. Both probiotics were singly cultivated in plates containing RPMI 1640 medium and T. canis larvae. S. boulardii and B. cereus var. toyoi cultures presented 97.6% and 95.7% of larvae with positive motility, respectively, and absence of color by the dye trypan blue, not representing significant difference to the control group (p > 0.05). We conclude that none of the probiotics showed in vitro effects on T. canis larvae and that the interaction with the intestinal mucosa is necessary for the development of the protective effect of S. boulardii.
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spelling pubmed-41050762014-07-24 PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE de Avila, Luciana Farias da Costa Telmo, Paula de Lima Martins, Lourdes Helena Rodrigues Glaeser, Thaís Aimeé Conceição, Fabricio Rochedo Leite, Fábio Pereira Leivas Scaini, Carlos James Rev Inst Med Trop Sao Paulo Brief Communication In a previous study our group found that the probiotic Saccharomyces boulardii was capable of reducing the intensity of infection in mice with toxocariasis. In order to assess whether the mechanism involved would be a direct action of the probiotic on Toxocara canis larvae, this study was designed. Both probiotics were singly cultivated in plates containing RPMI 1640 medium and T. canis larvae. S. boulardii and B. cereus var. toyoi cultures presented 97.6% and 95.7% of larvae with positive motility, respectively, and absence of color by the dye trypan blue, not representing significant difference to the control group (p > 0.05). We conclude that none of the probiotics showed in vitro effects on T. canis larvae and that the interaction with the intestinal mucosa is necessary for the development of the protective effect of S. boulardii. Instituto de Medicina Tropical 2013 /pmc/articles/PMC4105076/ /pubmed/24037293 http://dx.doi.org/10.1590/S0036-46652013000500012 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
de Avila, Luciana Farias da Costa
Telmo, Paula de Lima
Martins, Lourdes Helena Rodrigues
Glaeser, Thaís Aimeé
Conceição, Fabricio Rochedo
Leite, Fábio Pereira Leivas
Scaini, Carlos James
PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE
title PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE
title_full PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE
title_fullStr PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE
title_full_unstemmed PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE
title_short PROTECTIVE EFFECT OF THE PROBIOTIC Saccharomyces boulardii IN Toxocara canis INFECTION IS NOT DUE TO DIRECT ACTION ON THE LARVAE
title_sort protective effect of the probiotic saccharomyces boulardii in toxocara canis infection is not due to direct action on the larvae
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105076/
https://www.ncbi.nlm.nih.gov/pubmed/24037293
http://dx.doi.org/10.1590/S0036-46652013000500012
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