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USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS

SUMMARY: It is important to develop new methods for diagnosing relapses in the co-infection of visceral leishmaniasis (VL) and HIV to enable earlier detection using less invasive methods. We report a case of a co-infected patient who had relapses after VL treatment, where the qualitative kDNA PCR sh...

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Autores principales: Nicodemo, Antonio Carlos, Amato, Valdir Sabbaga, Tuon, Felipe Francisco, de Souza, Regina Maia, Okay, Thelma Suely, Braz, Lúcia Maria Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105093/
https://www.ncbi.nlm.nih.gov/pubmed/24213198
http://dx.doi.org/10.1590/S0036-46652013000600011
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author Nicodemo, Antonio Carlos
Amato, Valdir Sabbaga
Tuon, Felipe Francisco
de Souza, Regina Maia
Okay, Thelma Suely
Braz, Lúcia Maria Almeida
author_facet Nicodemo, Antonio Carlos
Amato, Valdir Sabbaga
Tuon, Felipe Francisco
de Souza, Regina Maia
Okay, Thelma Suely
Braz, Lúcia Maria Almeida
author_sort Nicodemo, Antonio Carlos
collection PubMed
description SUMMARY: It is important to develop new methods for diagnosing relapses in the co-infection of visceral leishmaniasis (VL) and HIV to enable earlier detection using less invasive methods. We report a case of a co-infected patient who had relapses after VL treatment, where the qualitative kDNA PCR showed a good performance. The kDNA PCR seems to be a useful tool for diagnosing VL and may be a good marker for predicting VL relapses after treatment of co-infected patients with clinical symptoms of the disease.
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spelling pubmed-41050932014-07-24 USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS Nicodemo, Antonio Carlos Amato, Valdir Sabbaga Tuon, Felipe Francisco de Souza, Regina Maia Okay, Thelma Suely Braz, Lúcia Maria Almeida Rev Inst Med Trop Sao Paulo Case Report SUMMARY: It is important to develop new methods for diagnosing relapses in the co-infection of visceral leishmaniasis (VL) and HIV to enable earlier detection using less invasive methods. We report a case of a co-infected patient who had relapses after VL treatment, where the qualitative kDNA PCR showed a good performance. The kDNA PCR seems to be a useful tool for diagnosing VL and may be a good marker for predicting VL relapses after treatment of co-infected patients with clinical symptoms of the disease. Instituto de Medicina Tropical 2013 /pmc/articles/PMC4105093/ /pubmed/24213198 http://dx.doi.org/10.1590/S0036-46652013000600011 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nicodemo, Antonio Carlos
Amato, Valdir Sabbaga
Tuon, Felipe Francisco
de Souza, Regina Maia
Okay, Thelma Suely
Braz, Lúcia Maria Almeida
USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS
title USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS
title_full USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS
title_fullStr USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS
title_full_unstemmed USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS
title_short USEFULNESS OF kDNA PCR IN THE DIAGNOSIS OF VISCERAL LEISHMANIASIS REACTIVATION IN CO-INFECTED PATIENTS
title_sort usefulness of kdna pcr in the diagnosis of visceral leishmaniasis reactivation in co-infected patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105093/
https://www.ncbi.nlm.nih.gov/pubmed/24213198
http://dx.doi.org/10.1590/S0036-46652013000600011
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