MiRNA-221 negatively regulated downstream p27Kip1 gene expression involvement in pterygium pathogenesis

PURPOSE: MiRNAs are small noncoding RNAs that have been implicated in tumor development. They regulate target gene expression either by mRNA degradation or by translation repression. Activation of β-catenin has been linked to pterygium progression. Here, we hypothesize that β-catenin-associated miRN...

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Detalles Bibliográficos
Autores principales: Wu, Chueh-Wei, Cheng, Ya-Wen, Hsu, Nan-Yung, Yeh, Ken-Tu, Tsai, Yi-Yu, Chiang, Chun-Chi, Wang, Wei-Ran, Tung, Jai-Nien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105113/
https://www.ncbi.nlm.nih.gov/pubmed/25053875

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