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Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus
αβT cell development depends upon serial migration of thymocyte precursors through cortical and medullary microenvironments, enabling specialized stromal cells to provide important signals at specific stages of their development. Although conventional αβT cells are subject to clonal deletion in the...
Autores principales: | Cowan, Jennifer E., McCarthy, Nicholas I., Parnell, Sonia M., White, Andrea J., Bacon, Andrea, Serge, Arnauld, Irla, Magali, Lane, Peter J. L., Jenkinson, Eric J., Jenkinson, William E., Anderson, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105241/ https://www.ncbi.nlm.nih.gov/pubmed/24990081 http://dx.doi.org/10.4049/jimmunol.1400993 |
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