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Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells
BACKGROUND: The characterization of induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) routinely includes analyses of chromosomal integrity. The belief is that pluripotent stem cells best suited to the generation of differentiated derivatives should display a euploid karyotype; a...
Autores principales: | Noto, Fallon K, Determan, Megan R, Cai, Jun, Cayo, Max A, Mallanna, Sunil K, Duncan, Stephen A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105394/ https://www.ncbi.nlm.nih.gov/pubmed/25002137 http://dx.doi.org/10.1186/1756-0500-7-437 |
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